Pasteurization could be translated as the process of heating of a fluid at a moderate temperature for a definite period of time to destroy undesirable microorganisms without changing to any extent the chemical composition.

As an example pasteurization could be found in dairy milk product. In pasteurization of milk, pathogenic organisms are invariably destroyed by heating at 62° C for a duration of 30 minutes, or by ‘flash’ heating to higher temperatures for less than 1 minute, which is otherwise known as high-temperature short time (HTST) pasteurization.
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Pasteurization refers to ‘the process of heating of a fluid at a moderate temperature for a definite period of time to destroy undesirable microorganisms without changing to any extent the chemical composition.’

Example. In pasteurization of milk, pathogenic organisms are invariably destroyed by heating at 62° C for a duration of 30 minutes, or by ‘flash’ heating to higher temperatures for less than 1 minute, which is otherwise known as high-temperature short time (HTST) pasteurization.
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Application of pharmaceutical principles to drug dosage forms is illust rated when drug dosage forms are categorized according to their physical state, degree of heterogeneity, and chemical composition. The usual relevant states of matter are gases, liquids, and solids. Intermolecular forces of attraction are weakest in gases and strongest in solids. Conversions from one physical state to another can involve simply overcoming intermolecular forces of attraction by adding energy (heat) . Chemical composition can have a dramatic effect on physicochemical properties and behavior. For this reason, it is necessary to distinguish between polymers, or macromolecules, and more conventional ( i .e., smaller) molecules, or micromolecules.
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